The Role of ABO Histo-Blood Group Antigens in Viral Infections
نویسندگان
چکیده
منابع مشابه
ABO and FUT2 Genetic Transcription Effects on ABH Histo-blood Group Antigens in Lung Cancer Patients
Lung cancer is one of the major health issues in China and the burden is getting serious. Aging is the main cause for the increasing incidence and mortality of lung cancer (Chen et al., 2010; Chen et al., 2011). There are more than one-hundred recognized blood group systems (BGA), containing more than 500 antigens. The ABO (including A, B, H antigens) and Lewis (Lea, Leb, Lex, Ley) systems are ...
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ABO histo-blood group antigens have been postulated to modify pathogen spread through the action of natural antibodies and complement. The antigens are generated by a polymorphic glycosyltransferase encoded by 2 dominant active and a recessive inactive allele. In this study we investigated whether ABO sugars are incorporated into the envelope of HIV-1 virions. HIV vectors derived from cells exp...
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متن کاملHIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complement-mediated inactivation.
ABO histo-blood group antigens have been postulated to modify pathogen spread through the action of natural antibodies and complement. The antigens are generated by a polymorphic glycosyl-transferase encoded by 2 dominant active and a recessive inactive allele. In this study we investigated whether ABO sugars are incorporated into the envelope of HIV-1 virions. HIV vectors derived from cells ex...
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ژورنال
عنوان ژورنال: Trends in Glycoscience and Glycotechnology
سال: 2005
ISSN: 0915-7352,1883-2113
DOI: 10.4052/tigg.17.285